Steven Van Cott
A Spokane native helping the community find safer alternatives such as CBD.
Is CBD Oil Safe?
Many people wonder if CBD Oil (also known as Cannabidiol) can benefit them. Emerging research about this single molecule suggests that there are several imbalances in the human body which CBD can assist. Due to prohibition against Cannabis and Hemp research, many fundamental questions about CBD and its exact mechanism of action still have yet to be completely elucidated. However, consider this: Several pharmaceutical drugs treating symptoms such as depression and anxiety, those approved by the drug-czars such as the FDA, still do not have complete and scientifically-validated data on their mechanisms either. For example, a recent article from Newsweek reported that antidepressants will not work for 30% of the population due to newly discovered genetic and neuronal differences in the brains of these individuals. This translates to approximately 100 million people in the U.S. alone, who will not respond to these drugs. In addition to a lack of efficacy (meaning the drug will not produce it's intended effects), antidepressants exhibit many well-known side-effects such as weight gain, constipation, sexual dysfunction, and possibly the loss of life due to suicidal thoughts.
On the other hand, CBD does not seem to confer these serious side-effects and can safely be administered because of its wide Therapeutic Index. Taking a bit too much CBD may lead to calmness, which could be beneficial to the 35% of adults who suffer from insomnia. Another misconception is that CBD will get you high like the other main constituent of Cannabis, d-9 THC, or delta-9-tetrahydrocannabinol. CBD, or Cannabidiol, will not effect any motor functions or your ability to operate machinery. This is because CBD, unlike its cousin THC, does not bind to the same brain regions which lead to Cannabis' notorious euphoria. When you take CBD, such as in a CBD-isolate and MCT (Medium-Chain Triglyceride) tincture under your tongue, the CBD binds preferentially with cells that operate through your immune system, including white blood cells, which assist the body in fighting off infection and disease. This means that you can receive the benefits of CBD without dealing with the psychotropic effects that THC can cause.
What is CBD Oil used for?
To begin with, we just want to point out that CBD is not a"Miracle Cure-All" which several advocates may claim. CBD is simply a natural alternative that may provide relief to many people suffering from the debilitating effects of pain, anxiety, insomnia, as well as the side-effects of medications, which so often precipitate other symptoms and disease-states. There is also preliminary research showing that CBD may promise revolutionary changes with regards to how we think about diseases such as:
• Alzheimer's: https://www.ncbi.nlm.nih.gov/pubmed/24256258
• Parkinson's Disease: https://www.ncbi.nlm.nih.gov/pubmed/25237116
• ADHD: https://www.ncbi.nlm.nih.gov/pubmed/22495620
• Migraines: https://www.ncbi.nlm.nih.gov/pubmed/20353780
• Stress: https://www.ncbi.nlm.nih.gov/pubmed/20439721
• Mood Disorders: https://www.ncbi.nlm.nih.gov/pubmed/23108553
• Multiple Sclerosis (MS): https://www.ncbi.nlm.nih.gov/pubmed/23851307
• PTSD: http://onlinelibrary.wiley.com/doi/10.1002/da.22031/abstract
• Autism: https://www.ncbi.nlm.nih.gov/pubmed/23585028
• Schizophrenia: https://www.ncbi.nlm.nih.gov/pubmed/22832859
• Rheumatism: http://www.theroc.us/researchlibrary/Clinical%20Implications%20for%20Cannabinoid%20Use%20in%20the%20Rheumatic%20Diseases.pdf
• Arthritis: https://www.ncbi.nlm.nih.gov/pubmed/10920191
• Traumatic Brain Injury (TBI): https://www.ncbi.nlm.nih.gov/pubmed/22659086
• Neurodegeneration: https://www.ncbi.nlm.nih.gov/pubmed/22625422
• Fibromyalgia: https://www.ncbi.nlm.nih.gov/pubmed/18404144
How does CBD Work?
CBD acts primarily by indirectly affecting what is known as the Endocannabinoid System, or ECS for short. This system is made up of two main chemicals found naturally in your body, known as Anandamide (which means 'Bliss' in Sanskrit) and 2-Arachidonoyl Glycerol, or 2-AG. Discovered in 1992 by a team of Isreali researchers headed by Raphael Mechoulam, the ECS has been gaining ground in areas of medical research for the past 27 years. What we now know is that ECS plays an integral part in our body's ability to fend off disease, reduce inflammation, and maintain balance in the body, known as homeostasis. CBD works to return the body to a state of homeostasis by modulating the ECS and thus assisting our bodies in dealing with inflammation in a healthier way than modern pharmaceutical drugs.
In addition to Anandamide and 2-AG, we find the primary receptors which make up the endocannabinoid system to include CB1 and CB2. An analogy for how Anandamide and 2-AG interact with the CB1 and CB2 receptors is to use something we are all familiar with: Airplanes. If Anandamide and 2-AG are airplanes, then the CB1 and CB2 receptors are the landing runways. This where the metaphor stops. Due to the specific-binding of our body's receptors, only molecules (or airplanes from our above example) which look like 2-AG and Anandamide can land on the CB1 or CB2 receptors (runways). CBD happens to be one of those look-alikes and seems to prefer docking on the CB2 receptor than the CB1 receptor. It is this property of CBD which leads to its ability of assisting our body in returning to its natural state of homeostasis.
Many of our customers at CBD of Spokane are dealing with very real pain. Everything from fibromyalgia, to multiple sclerosis, to neuropathy. When they walk in our door we may not be able to visibly see what they are going through, but we know that many of them have tried opiates, gabapentin, and several other drugs that can bring your body out of alignment. When the big pharmaceutical industry have failed to bring relief from pain, several times we receive feedback that CBD has been working wonders in their life. A two-pronged approach seems to work best for people dealing with systemic (all-over) pain, along with localized (points on the body such as joints) where pain arises. What this means is to use a tincture to fight inflammation (many times the underlying cause of pain) as well as salve or cream to put on those achy knees, feet, or neck. Ask our qualified team at CBD of Spokane for the specific tinctures and topicals to use for your individual needs.
At CBD of Spokane, we have several customers using CBD for anxiety of all severities. Whether you are just dealing with a little social phobia or locking yourself away in your house or apartment to get away from anxious thoughts, CBD has been shown in scientific studies to affect 5-HT1A receptors which can assist you with feeling more relaxed. When you have severe anxiety, you need relief quickly (ie seconds to minutes). Generally, CBD tinctures provide quick access to the blood stream, as opposed to edibles or topicals. Visit our shop today for a range of tinctures which may lead to a calmer version of yourself.
Insomnia is the inability to get to sleep and stay asleep properly. CBD has been shown scientifically to interact with our Circadian Rhythm, the thing that get us to sleep at a regular time and wake up at a regular time. It is integral to our health and well-being. When we don't sleep, we miss out on so many of the health benefits of sleep and don't repair our bodies properly. When someone enters our shop unable to fall and stay asleep, they may resort to using CBD for their insomnia. In these cases, a full-spectrum tincture (meaning it contains CBD and trace amounts, 0.3%, of THC) may be just the thing to get a good night's sleep. Click the button below this post in order to find our CBD tinctures and other CBD products today!